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In the United States, spinal metastases affect more than 150,000 individuals per year. Benign spinal tumors and vascular malformations constitute more than 4,000 cases per year. While surgery, chemotherapy and radiation therapy have historically been the standard of care, the CyberKnife® has emerged as a revolutionary treatment for delivering spine radiosurgery – rapidly delivering proven tumor control and durable pain relief.

Unprecedented Targeting Accuracy

Spinal tumors, even when immobilized, can shift nearly 4 millimeters over just a 15-minute treatment period. Where conventional technologies such as IGRT and cone beam CT often provide image guidance for pre-treatment set-up, target movements during the treatment remain unrecognized, which may result in an increased risk of toxicity to sensitive structures.

Using advanced robotic technology the CyberKnife is the only system to utilize continual image guidance to automatically track, detect and correct for intra-fraction target movements. With the CyberKnife, radiosurgical accuracy is maintained throughout the treatment – from the first beam to the last. With these unique capabilities, the CyberKnife has demonstrated an unprecedented 0.53 mm targeting accuracy treating spinal lesions in independent, peer-reviewed studies.*

For more than 30 years, radiosurgery technical research and clinical studies have demonstrated that a large array of uniquely angled beams enhances the dose conformality while reducing the risks of dose toxicity. Unconstrained by the clockwise/counter-clockwise gantry rotations of conventional radiation therapy equipment, the CyberKnife extends these proven benefits by delivering diverse non-coplanar treatment routinely in daily clinical practice Unlike the 7 to 9 beam plans common with gantry-based systems, a typical CyberKnife treatment includes more than 100 uniquely angled, highlyfocused beams per fraction.

Where isocentric treatment delivery is common for treating large radiotherapy fields and spherical targets, this technique is often not optimal for treating targets of complex shapes – especially with radiosurgical doses and when radiosensitive structures are in close proximity. As the only system capable of delivering both isocentric and non isocentric treatments, the CyberKnife has an unparalled ability to precisely sculpt delivered dose around sensitive critical structures.

Completely Non-invasive Tumor Tracking

The CyberKnife has rendered implanted fiducials and external markers unnecessary. Advanced image enhancement and image registration technology allow spinal tumors to be targeted and tracked based entirely on information provided by the surrounding bony anatomy. Rather than treating the spine as a rigid body, the CyberKnife tracks the complex motion of individual spinal segments to ensure radiosurgical accuracy throughout the treatment. Furthermore, this completely noninvasive capability applies to nearly 100 percent of spine cases at all levels of the spine.

Proven capabilities, proven results

As the pioneer of spinal radiosurgery, the CyberKnife is now recognized as the premier solution for safe and effective treatment delivery. Then non-coplanar, non-isocentric approach only available with the CyberKnife has been clinically proven to provide significant and durable pain relief, In fact, a recent study of 500 cases from the university of Pittsburgh Medical Center demonstrated 88 percent effective tumor control and 86 percent long term pain improvement with single fraction treatments using CyberKnife – all without a single neurological complication.